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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Exosomes derived from human menstrual blood-derived stem cells alleviate fulminant hepatic failure

Fig. 6

MenSC-Ex transplantation enhanced survival rates and improved liver function in a D-GalN/LPS-induced FHF mouse model. a Survival curves after mice were injected with D-GalN/LPS (n = 10). b and c Serum levels of ALT and AST were measured at 6 h after stimulation with D-GalN/LPS. d-f Liver levels of the IL-6, IL-1β, and TNF-α mRNAs were also detected using real-time RT-PCR at 6 h after the nice were injected with D-GalN/LPS. g-i Serum levels of IL-6, IL-1β, and TNF-α were determined using ELISA. j Liver sections were obtained from D-GalN/LPS-induced mice and analyzed using H&E staining (n = 10 per group, **p < 0.01). Scale bar = 50 μm

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