Fig. 7
From: Exosomes derived from human menstrual blood-derived stem cells alleviate fulminant hepatic failure
MenSC-Ex inhibited hepatocyte apoptosis and caspase-3 expression in D-GalN/LPS-induced FHF. A TUNEL assay showing liver sections at 6 h after D-GalN/LPS-induced FHF. Apoptotic cells were stained with green fluorescence, and nuclei were stained red, indicating PI. Scale bar = 50 μm (B). Analysis of genomic DNA fragmentation in liver tissues obtained at 6 h after D-GalN/LPS injection in the (a) normal group, (b) model group, (c) silymarin group, and (d) MenSC-Ex group. C Immunohistochemical analysis of caspase-3 expression in apoptotic liver cells at 6 h after D-GalN/LPS injection. Scale bar = 50 μm (D) The expression of caspase-3 was evaluated in apoptotic liver cells at 6 h after D-GalN/LPS injection (**p < 0.01)