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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Optimizing mesoderm progenitor selection and three-dimensional microniche culture allows highly efficient endothelial differentiation and ischemic tissue repair from human pluripotent stem cells

Fig. 7

Endothelial induced MESP1 progenitor cells differentiated into blood vessels in critical limb ischemia mouse. a Frozen sections from control- treated ischemic hindlimb, no human CD31 (hCD31) and human nuclei (hNA) can be seen on day 28. Scale bar: 100 μm. b and c Frozen sections from Cell + GM transplanted hindlimb showed clear hCD31 and hNA staining (b), and hCD31 and α-SMA co-localization (c) at day 28. Scale bars: 100 μm

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