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Table 1 Comparison between donor characteristics and successful CB-MSC isolation

From: Generation of mesenchymal stromal cells from cord blood: evaluation of in vitro quality parameters prior to clinical use

 

All samples (n = 50)

MSC-positive isolation (n = 22)

MSC-negative isolation (n = 28)

p value

Median time after delivery, hours (range)

5 (2–24)

5 (2–24)

7 (2–24)

0.799°

Median TNC × 106 (range)

696 (276–1700)

675 (383–1290)

700 (276–1700)

0.662°

Median MNC × 106 (range)

191 (14–615)

200 (85–615)

191 (14-–62)

0.703°

CB median volume, ml (range)

41 (18–87)

43 (22–87)

40 (18–78)

0.323§

Median gestational time, days (range)

273 (259–292)

273 (264–292)

275 (259-–92)

0.288°

Median mother age, years (range)

35 (26–45)

34 (29–41)

35 (26–45)

0.799§

Pluriparity

27 (54%)

11 (50%)

16 (57.1%)

0.198*

Male babies

27 (54%)

14 (63.6%)

13 (46.4%)

0.264*

Median baby weight, grams (range)

3390 (2430–4460)

3335 (2700–4460)

3405 (2430-–090)

0.674§

Mater/baby blood group match

26 (52%)

15 (68.2%)

11 (39.3%)

0.052*

Cesarean birth

14/48 (29.2%)

7/20 (35%)

7/28 (25%)

0.528*

  1. Abbreviations: MSC mesenchymal stromal cells, TNC total nucleated cells, MNC mononuclear cells, CB cord blood
  2. Statistical tests:
  3. °Mann-Whitney U test
  4. §Unpaired t test
  5. *The differences between the categorical variables were computed by the Fisher exact test