Fig. 6

MSC administration increases local and systemic levels of key hepatic regenerative inductors, after 70% hepatectomy. Hepatic mRNA levels of (a) interleukins (TNF-α, IL-6, IL-1β, IL-4, and IL-10) and (b) pro-regenerative trophic factors (EGF, HGF, IGF-1, and bFGF) quantified by RT-qPCR, 2 days after-Hpx. Quantitative analysis of plasmatic levels of the same (c) interleukins and (d) pro-regenerative trophic factors determined by Luminex Multiplex system, 2 days after-Hpx. All data are presented as mean ± SEM (n = 8), a p < 0.05 vs. normal pre-Hpx; b p < 0.05 vs. normal + Vh; c p < 0.05 vs. obese pre-Hpx and d p < 0.05 vs. obese + Vh