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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Metformin promotes the survival of transplanted cardiosphere-derived cells thereby enhancing their therapeutic effect against myocardial infarction

Fig. 7

Metformin (MET) treatment increased phosphorylation of AMP-activated protein kinase (AMPK)/endothelial nitric oxide synthase (eNOS) in CDCs. Representative blots (a1) and quantification (a2) of AMPK phosphorylation. AMPK phosphorylation was represented as the ratio of phosphorylated α-AMPK at Thr-172 to total AMPK of CDCs. Representative blots (b1) and quantification (b2) of eNOS phosphorylation. eNOS phosphorylation was represented as the ratio of phosphorylated eNOS at Ser-1177 to total eNOS of CDCs. Data were analyzed by one-way ANOVA with post-hoc comparisons by the Tukey’s test. *P < 0.05 vs. control; # P < 0.05 vs. H2O2. CC compound C

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Stem Cell Research & Therapy

ISSN: 1757-6512