Reference | LOE | Sample size (n) | Subjects | Donor sites | Outcome: clinical | Outcome: ADSC yield | Outcome: differentiation potential |
---|---|---|---|---|---|---|---|
Small et al. 2014 [123] | 2 | 73 | Fat transfer to reconstructed breasts | Two donor sites: abdomen and thighs | Measured pre- and post-operative 3D scans to assess volumetric changes. No statistically significant difference between donor sites | Â | Â |
Lim et al. 2012 [124] | 2 | 27 | Patients with craniofacial microsomia, Treacher Collins syndrome | Two groups: abdomen and non-abdominal sites | Measured 2D analysis using pre-op and post-op photographs. Adipose tissue from abdominal or non-abdominal sources equally corrected asymmetry | Â | Â |
Padoin et al. 2008 [32] | 2 | 25 | Liposuction aspirate | Six donor sites: upper abdomen, lower abdomen, knee, inner thigh, flank and trochanteric region | Â | The cell concentration in lower abdomen and inner thigh was statistically higher than in other areas | Â |
Geissler et al. 2014 [27] | 2 | 24 | Liposuction aspirate | Three donor sites: lower abdomen, thigh and flank | Â | In younger patients, adipocyte viability was greater in the lower abdomen than in the flank; in older patients, this difference was not seen. Higher viability of flank adipocytes in the older group compared with younger group | Â |
Jurgens et al. 2008 [64] | 2 | 22 | Liposuction aspirate | Two donor sites: abdomen and hip/thigh | Â | ADSC yield significantly higher from abdominal aspirate | No statistical difference in absolute number of nucleated cells and differentiation capacity |
Rohrich et al. 2004 [67] | 2 | 5 | Liposuction aspirate | Three donor sites: knee, flank and abdomen | Â | No statistical difference in viability | Â |
Choudhery et al. 2014 [120] | 2 | 3 | Liposuction aspirate | Five donor sites: abdomen, flank, thigh, scarpas fascia, submental jowl | Â | No statistical difference in proliferation | Â |
Di Taranto et al. 2015 [125] | 2 | 1 | Liposuction aspirate | Superficial versus deep abdominal fat | Â | Â | Superficial fat increased differentiation capacity |
Ullmann et al. 2005 [68] | 2 | 45 nude mice (15 in 3 groups) | Fat from one woman injected into 3 groups with 15 nude mice each | Three donor sites: abdomen, breast and thigh | Â | Fat compared for viability and volume retention showing no statistical difference | Â |
Li et al. 2013 [66] | 2 | 30 nude mice (6 in 5 groups) | Fat from six women injected into nude mice | Five donor sites: flank, upper abdomen, lower abdomen, medial thigh, lateral thigh viability | . | Cell count and assay by flow cytometry and graft evaluation at 12Â weeks post-transplantation and showed no statistical difference | Â |