Fig. 5
a Representative CO2 reactivity map from each group at 28 days post-middle cerebral arterial occlusion (MCAO). The region encircled by the green line is the ROI, defined by the stroke lesion on the corresponding T2 map. The color scale bar indicates percentage change in cerebral blood flow (CBF) ranging from 1% to 100% (yellow–red). b Quantification of percentage CBF changes responding to 5% CO2 challenge from ROI (n = 6 per group, mean ± SEM). *P < 0.05, versus the PBS vehicle; # P < 0.05, ## P < 0.01, versus contralateral homologous regions. c CO2 induced percentage change in CBF were analyzed separately on normal, hyper-, and hypoperfusion areas of ROI (n = 6 per group, mean ± SEM). *P < 0.05, versus the PBS vehicle; # P < 0.05, ## P < 0.01, versus normal perfusion of the same group. hUCB human umbilical cord blood, MNC mononuclear cell