Fig. 7

Blood glucose levels in streptozotocin (STZ)-induced diabetic mice injected intraperitoneally with or without muscle-derived stem cells (MDSC). Six-month-old male C57Bl6 were injected intraperitoneally with a solution of STZ at 150 mg/kg and blood glucose levels were measured at the tail tip twice per week at 2 pm (at resting day time). After 7 days, when blood glucose levels had risen above 450 mg/dl, half the mice (n = 4) were injected intraperitoneally with 300,000 MDSC in 200 μl saline solution prepared from consanguineous female Bl6 mice and the other half were injected with 0.9% NaCl solution only (n = 4). Shown are the average blood glucose levels measured and plotted for each time point revealing a decrease of the glycemia in MDSC-injected mice by 7–10 days after intraperitoneal injection of the stem cells