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Table 2 Different expression of genes at the 4-week follow-up in stem cell treated patients compared to control patients

From: Autologous bone marrow-derived cell transplantation in decompensated alcoholic liver disease: what is the impact on liver histology and gene expression patterns?

Accession number Gene name Affymetrix fold-expression p value Nanostring fold-expression p value
Macrophages, inflammation, and chemotaxis
 NM_001040059, NM_001251 CD68
CD68 molecule
1.11 0.5874 5.19 0.0011
 NM_002993 CXCL6 (chemokine (C-X-C motif) ligand 6) 2.03 0.0327 3.42 0.2015
 NM_002985 CCL5 (chemokine (C-C motif) ligand 5) 1.53 0.0411
 NM_033439 IL33 (interleukin 33) 1.53 0.0336
 NM_000331, NM_001127380, NM_001178006, NM_030754, NM_199161 SAA-1 (serum amyloid A1) 1.73 0.0692 2.68 0.0455
 NM_001127380, NM_030754 SAA-2 (serum amyloid A2) 1.12 0.7873 3.11 0.0202
 NM_004887 CXCL14 (chemokine (C-X-C motif) ligand 14) –2.13 0.0458 –6.32 0.1257
Liver regeneration and stem cells
 NM_000601, NM_001010931, NM_001010932, NM_001010933, NM_001010934 HGF (hepatocyte growth factor) 1.11 0.4825 7.50 0.0019
 NM_016639 TNFRSF12A (tumor necrosis factor receptor superfamily, member 12A) 1.15 0.4973 1.08 0.9551
 NM_003122 SPINK1 (serine peptidase inhibitor, Kazal type 1) 4.29 0.0446 19.95 0.0979
 NM_005556 CK7(keratin 7) –1.11 0.7284 –3.38 0.3841
 NM_002276 CK19(keratin 19) 1.04 0.8957 –2.15 0.5533
 NM_002838, NM_080921, NM_080923 PTPRC (CD45) (protein tyrosine phosphatase, receptor type, C) 1.52 0.0473 8.98 0.0260
Fibrosis
 NM_000088 COL1A1
(collagen, type I, alpha 1)
1.38 0.1405 10.54 0.0101
Other
 NM_001142466, NM_133443 GPT2 –1.54 0.0201
 NM_001190463, NM_001902, NM_153742 –1.83 0.0365
 NM_001195728, NM_004171 SLC1A2 (solute carrier family 1 (glial high affinity glutamate transporter), member 2) –2.22 0.0147
  1. Values shown in bold are significant at p < 0.05