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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Autophagy mediates the beneficial effect of hypoxic preconditioning on bone marrow mesenchymal stem cells for the therapy of myocardial infarction

Fig. 2

Effect of hypoxic preconditioning (HPC) on the viability and paracrine mechanism of BM-MSC Fluc+GFP+. a Representative in vitro BLI results of BM-MSCFluc+GFP+ with HPC for 0 h, 12 h, 24 h, 36 h, and 48 h under normal conditions and after hypoxia/serum deprivation (H/SD). b The quantification of BLI assays. c MTT assay demonstrated the effects of HPC (0 h, 12 h, 24 h, 36 h, and 48 h) on viability of BM-MSCFluc+GFP+. d ELISA assay demonstrated the levels of vascular endothelial growth factor (VEGF) (d), basic fibroblast growth factor (bFGF) (e), insulin-like growth factor-1 (IGF-1) (f), and hepatocyte growth factor (HGF) (g) within BM-MSCFluc+GFP+ supernatants. Data are expressed as the mean ± SEM; n = 5; *p < 0.05

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