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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: The crosstalk between vascular MSCs and inflammatory mediators determines the pro-calcific remodelling of human atherosclerotic aneurysm

Fig. 4

Adipogenic differentiation of AAA-MSCs. a Representative Oil Red O staining of ha-MSCs and AAA-MSCs showed the formation of lipid droplets after induction with adipogenic medium for 14 days. b Real-time PCR performed on differentiated MSCs revealed significant up-regulation of PPAR-γ in AAA-MSCs following induction. Results are expressed as fold changes relative to undifferentiated ha-MSCs and are representative of at least three independent experiments. *p < 0.05. AD adipogenic, PPAR-γ peroxisome proliferation activated receptor gamma, ha-MSC healthy aortic MSC, AAA-MSC abdominal aortic aneurysm MSC, MSC mesenchymal stem cell, ctrl control

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