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Table 1 Senescence characteristics and telomere length of WJ-MSCs and BM-MSCs

From: Differential expression of cell cycle and WNT pathway-related genes accounts for differences in the growth and differentiation potential of Wharton’s jelly and bone marrow-derived mesenchymal stem cells

Passages

SA-β-gal positive cells (%)a

Mean telomere lengtha

 

WJ-MSCs

BM-MSCs

P

WJ-MSCs

BM-MSCs

P

P2

10.28 ± 5.73

25.82 ± 17

0.0169

11,958 ± 1687

10,530 ± 2244

N.S.

P6

15.14 ± 9.73

39.33 ± 22.46

0.0327

10,128 ± 1317

8901 ± 870.9

N.S.

P10

24.09 ± 11

59.14 ± 15.69

0.0001

8529 ± 1619

8212 ± 1486

N.S.

  1. Comparisons in each indicated passage (P; P2, P6, P10) between WJ-MSCs (n = 18) and BM-MSCs (n = 18) have been performed by the nonparametric Mann–Whitney U test and the statistically significant P values are shown
  2. Abbreviations: WJ-MSCs Wharton’s jelly-mesenchymal stem cells, BM-MSCs bone marrow-mesenchymal stem cells, SA-β-gal senescence-associated β galactosidase, N.S. no statistically significant difference
  3. aThe data are expressed as means ± 1 standard deviation