Fig. 7
From: Exosomes from mesenchymal stem cells induce the conversion of hepatocytes into progenitor oval cells
MSC-secreted exosomes induced EpCAMhigh small oval cells from CD26+ hepatocytes. Characterization of MSC-secreted exosomes by a CD9 and CD63 expression, b dynamic light scattering analysis, and c TEM. d CD26+ hepatocytes were sorted and treated with control medium and 50 μg/ml MSC-secreted exosomes for 14 days. e The cells were stained with EpCAM immunostaining. f The normalization and quantification of EpCAM expression. * P < 0.05; ** P < 0.01. Sup. Supernatant