Skip to main content

Table 1 Genetic screening by karyotype and CGH array

From: High quality clinical grade human embryonic stem cell lines derived from fresh discarded embryos

Line Karyotype CGH summary Variants of unknown clinical significance 20q11.21-acquired culture adaptation
MAN10 p14* Normal 46 XY Male profile arr[hg19] 10q21.1(54,584,623-57,696,041)x1  
MAN11 p14 46,XX,t(5;9) [13]/46,XX [7] Female profile: arr[hg19] Xp22.33(586,009-673,701)x3  
MAN12 p14 Normal 46 XY Male profile: None detected  
MAN13 p24 Normal 46 XY Male profile: arr[hg19] Xp11.21(56,301,224-56,395,414)x2 arr[hg19] 20q11.21(29,873,327-30,971,568)x3
MAN14 p20 Normal 46 XX Female profile: None detected arr[hg19] 20q11.21(29,877,879-30,889,947)x4
MAN15 p16 Normal 46 XY Male profile arr[hg19] 2p15(63,514,505-63,702,363)x1, 6q26(162,654,003-163,000,271)x3  
MAN16 p16 Normal 46 XY Male profile: None detected  
  1. *Passage number at which cells were analysed
  2. CGH comparative genomic hybridisation