Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells

Fig. 5

Effects of NPC exosomes on NPC-specific protein expression in BM-MSCs. (a) Gene expression of ACAN (a), SOX-9 (b), COL2A1 (c), HIF-1α (d), CA12 (e) and KRT19 (f) in BM-MSCs was significantly upregulated by NPC exosomes with time. Expression of these genes was normalized to β-actin and control (BM-MSCs alone). Values are the mean ± SD. n = 3.*P < 0.05, **P < 0.01, ***P < 0.001. (b) NPC-specific protein expression in BM-MSCs described in (a) analyzed by western blot analysis. (c) TGF-β in NPC exosomes. NPC nucleus pulposus cell

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512