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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: ERK signaling is required for VEGF-A/VEGFR2-induced differentiation of porcine adipose-derived mesenchymal stem cells into endothelial cells

Fig. 4

Phosphorylation of JNK, p38, and ERK after 10 days of AMSC differentiation to ECs. Western blot detection of p-JNK (a), p-p38 (b), and p-ERK1/2 (c) in AMSC lysates after 10 days of AMSC stimulation for EC differentiation with EBM (control), EGM, EGM + MMP-2 siRNA, and EGM + MMP-14 siRNA. Phospho-proteins were normalized to their total protein expressions. *p < 0.05, **p < 0.01, ***p < 0.001. EBM endothelial cell basal medium, EGM endothelial cell growth medium, MMP matrix metalloproteinase, ERK extracellular signal-regulated kinase, JNK c-Jun NH2-terminal kinase, p38 stress activated protein kinase-2

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Stem Cell Research & Therapy

ISSN: 1757-6512