Fig. 3

Invasion assay of ASDCs and BRCAs alone and in co-culture. Invasive capacity was measured as optical density at 650 nm. a ADSC-EVSA-T co-culture: co-cultured ADSCs showed a significantly higher invasive activity than in monoculture (p = 0.039). There was no significant change in EVSA-T BRCA invasive activity in co-culture. b ADSC-MCF-7 co-culture: there was no significant change in ADSC or MCF-7 invasive activity in co-culture compared to the respective monoculture (p > 0.05). c ADSC-MDA-MB-231 co-culture: co-cultured ADSCs showed a significantly higher invasive activity than in monoculture (p = 0.039). There was no significant change in MDA-MB-231 BRCA invasive behavior in co-culture. d ADSC-SK-BR-3 co-culture: co-cultured ADSCs showed a significantly higher invasive activity than in monoculture (p = 0.023). There was no significant change in SK-BR-3-BRCA invasive behavior in co-culture. e ADSC-ZR75-30 co-culture: there was no significant change in ADSC or ZR75-30 invasive activity in co-culture compared to the respective monoculture (p > 0.05). f ADSC-pBRCA co-culture: there was no significant change in ADSC or pBRCA invasive behavior in co-culture compared to the respective monoculture (p > 0.05). Values are shown with standard deviations. ADSC adipose-derived mesenchymal stem cell