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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Tissue-specific bioactivity of soluble tendon-derived and cartilage-derived extracellular matrices on adult mesenchymal stem cells

Fig. 5

Effect of treatment with soluble ECMs on production of specific ECM components in MSC pellet cultures. Supplementation with TGF-β and cECM promoted deposition of sGAG, Collagen II, and Collagen X, while tECM enhanced Collagen I synthesis. Control consisted of MSC pellet culture without any medium supplement. Collagen II = red, Collagen I = green, Collagen X = green, nuclei = blue. Scale bar = 500 μm. cECM urea-extracted cartilage extracellular matrix, tECM urea-extracted tendon extracellular matrix, TGF transforming growth factor

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Stem Cell Research & Therapy

ISSN: 1757-6512