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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications

Fig. 3

TAF-MSCs show a similar expression profile compared with expanded MSCs derived from other tissues. a Schematic diagram showing the main steps of analysis for assessing the transcriptional similarities of enriched genes in TAF-MSCs and MSCs from adult sources. b Venn diagrams illustrate significant similarities in the gene expression profiles of TAF-MSCs, BM-MSCs, and AD-MSCs. Pink circles total number of significantly differentially expressed genes between TAF-MSCs and CB-Endo (≥1.5 fc and p < 0.05); blue circles total number of significantly differentially expressed genes between AD-MSCs and AD-Endo (left diagram), between BM-MSCs and HUVECs (middle diagram), or between BM-MSCs and BM-MSC-OB (right diagram). p value calculated by hypergeometric statistical test indicates the significance of the overlap between each analysis. AD-Endo adipose tissue-derived endothelial cell, AD-MSC adipose tissue-derived mesenchymal stromal cell, BM-MSC bone marrow-derived mesenchymal stromal cell, BM-MSC-OB BM-MSCs induced to differentiate to osteoblasts, CB-Endo cord blood-derived endothelial cell, HUVEC human umbilical vein endothelial cell, TAF-MSC term amniotic fluid-derived mesenchymal stromal cell

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Stem Cell Research & Therapy

ISSN: 1757-6512