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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Human adipose tissue mesenchymal stromal cells and their extracellular vesicles act differentially on lung mechanics and inflammation in experimental allergic asthma

Fig. 6

Total cell count and percentage of T cells (CD3+CD4+), Treg cells (CD4+CD25+Foxp3+), and eosinophils (Siglec-F+) in bronchoalveolar lavage fluid (BALF). Data are presented as means + SD of ten animals/group. CTRL mice sensitized and challenged with saline, OVA mice sensitized and challenged with ovalbumin, OVA-SAL OVA mice treated with saline, OVA-AD-MSC OVA mice treated with mesenchymal stromal cells derived from adipose tissue (AD-MSCs), OVA-EV OVA mice treated with extracellular vesicles derived from AD-MSCs. CTRL versus OVA-SAL (total cell count p < 0.0001, eosinophils p = 0.0006, Treg cells p < 0.0001, T cells p = 0.034)

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