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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Minocycline modulates NFκB phosphorylation and enhances antimicrobial activity against Staphylococcus aureus in mesenchymal stromal/stem cells

Fig. 4

Antibacterial activity of MSCs against SA and subsequent supernatant cytokine analysis. a Colony forming abilities of SA after 6 hours of coculture with media controls, MSCs, or MSCs pretreated with antibiotics. Presence of antibacterial peptide LL-37 (b), IL-6 (c), TNF-α (d), and MCP-1 e in MSC/SA cocultures. *p < 0.05, **p < 0.01, ***p < 0.005, ****p < 0.001. CFU colony forming unit, IL-6 interleukin-6, LL-37 cathelicidin-related antimicrobial peptide, MCP-1 monocyte chemotactic protein, MSC mesenchymal stromal/stem cell, SA Staphylococcus aureus, TNF-α tumor necrosis factor alpha, TSB tryptic soy broth

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Stem Cell Research & Therapy

ISSN: 1757-6512