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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Exosomes secreted by stem cells from human exfoliated deciduous teeth contribute to functional recovery after traumatic brain injury by shifting microglia M1/M2 polarization in rats

Fig. 5

Detection of mRNA expression of M1 and M2 phenotypic markers of microglia. a M1-associated markers CD11b, CD86, CD16, MHC II, and iNOS were significantly decreased after exosome treatment compared with the single LPS stimulation group. b M2-associated markers CD206, IL-10, and ARGINASE 1 were significantly increased after exosome treatment compared to the single LPS stimulation group. # P < 0.05 compared with non-activated microglia cells. * P < 0.05, ** P < 0.01, *** P < 0.001 compared with LPS-only treated cells. IL-10 interleukin-10, LPS lipopolysaccharide

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