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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Mesenchymal stromal cell therapy reduces lung inflammation and vascular remodeling and improves hemodynamics in experimental pulmonary arterial hypertension

Fig. 6

Real-time PCR analysis of biological markers associated with inflammation (interleukin (IL)-6, IL-10) (a, b), apoptosis (procaspase 3) (c), and antiapoptosis (B-cell lymphoma 2 (Bcl-2) and survivin) (d, e) in lung tissue. Lines represent medians, and whiskers are the interquartile range of seven animals in each group. Relative gene expression calculated as a ratio of the average gene expression level compared with the reference gene (36B4) and expressed as fold change relative to CTRL-SAL. Comparisons by Student’s t test followed by Bonferroni’s corrections for three comparisons (*p < 0.0167). CTRL control, MCT monocrotaline, SAL saline

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