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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Adjudin-preconditioned neural stem cells enhance neuroprotection after ischemia reperfusion in mice

Fig. 8

Adjudin-pretreated NSCs inhibited the oxidative stress after tMCAO. Modulation of oxidative stress gene expression in vivo. Relative mRNA expression of iNOS, catalase, and SOD2 in ipsilateral cortex (ac) and striatum (df) normalized to Rplp0 detected 3 days after cell transplantation. Western blot analysis of iNOS, catalase, and SOD2 protein levels in ipsilateral cortex and striatum 3 days after cell transplantation (g, h). Quantification of densitometric value of the protein bands of cortex (ik) and striatum (ln) normalized to the respective β-tubulin. n = 6 in each group. Data are mean ± SEM. *P < 0.05, **P < 0. 01, ***P < 0. 001. NSC neural stem cell, PBS phosphate-buffered saline

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