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Table 1 Characteristics of the included studies

From: Meta-analysis on the treatment of diabetic foot ulcers with autologous stem cells

Study

Mean age (years)

Participant cases (treatment group)

Stem cell type

Baseline ulcer size (cm2)

Cell number

Delivery method

Placebo

Follow-up duration (weeks)

Adverse events

Lu et al., 2011, China [18]

65

11

BMMNCs

4.3

NA

i.m.

N.S.

24

No

Lu et al., 2011, China [18]

63

11

BMMSCs

4.2

NA

i.m.

N.S.

24

No

Huang et al., 2005, China [19]

71

18

PBMNCs

2.7

3 × 109/leg

i.m.

PGE1

12

No

Kirana et al., 2012, Germany [20]

69

12

BMMNCs

9.6

3 × 108/leg

i.m.

No

45

No

Kirana et al., 2012, Germany [20]

71

12

BMTRCs

7.7

8 × 107/leg

i.m.

No

45

No

Han et al., 2010, Korea [21]

67

26

PLA cells

4.3

> 4 × 106/ulcer

Ad.us.ext.

No

8

No

  1. Ad.us.ext. ad usum externum (for external use), BMMNCs bone marrow-derived mononuclear cells, BMMSCs bone marrow-derived mesenchymal stem cells, BMTRCs bone marrow-enriched tissue repair cells, i.m. intramuscularly, NA not available, N.S normal saline, PBMNCs peripheral blood-derived mononuclear cells, PGE1 Prostaglandin E1, PLA human processed lipoaspirate