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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Combined platelet-rich plasma and lipofilling treatment provides great improvement in facial skin-induced lesion regeneration for scleroderma patients

Fig. 1

SSc adipose samples show peculiar features and different tissue morphology. a Representative H&E staining on paraffin-embedded sections of freshly isolated adipose tissue from healthy donors and SSc patients. Arrows indicate MSCs (black) and blood vessels (red). b CD271 positivity in freshly isolated SVF and long-term propagated AD-MSCs from healthy donors and SSc patients, performed by flow cytometry. Data are mean ± SD of three independent experiments. c Flow cytometry analysis of cell positivity percentage for CD271, CD44, CD29, CD9, CD90, and CD73, performed on AD-MSCs of healthy subjects (blue) and SSc patients (red). Percentage values in b and c represent the percentage of parent population. Bars represent mean ± SD of three independent experiments. *p < 0.05, ***p < 0.001, ns nonsignificant. AD-MSC adipose-derived mesenchymal stem cell, SSc systemic sclerosis, SVF stromal vascular fraction

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