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Table 4 Percentage reduction of VAS and ODI at 1, 3, 6, and 12 months post injection and ADC value improvement at 1, 6, and 12 months post injection

From: Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain: 1-year follow-up of a phase I study

Patient number Reduction in VAS (%) Reduction in ODI (%) ADC value
1 month 3 months 6 months 12 months 1 month 3 months 6 months 12 months Pre treatment 1 month 6 months 12 months
1 50 75 63 50 30 40 25 25 1060 1290 1410 1456.7
2 15 15 57 100 41 47 65 91 1423.3 1413.3 1180 1160
3 17 17 17 33 33 27 20 13 1230 1480 1050 1193.3
4 29 0 100 86 36 38 82 82 1056.7 1230 1116.7 1086.7
5 0 25 25 50 19 31 31 75 1623.3 1470 1516.7 1583.3
6 29 29 57 14 17 31 58 36 1036.7 875 ND ND
7 50 50 50 50 4 15 58 70 1173.3 992.3 1236.7 1063.3
8 33 67 50 50 25 31 59 63 834.3 800.7 998.7 965
9 50 33 50 50 38 25 19 56 1243.2 1366.7 1470 1496.7
10 14 43 29 43 50 48 60 57 1034.6 1226.7 1036.7 1053.3
  1. VAS visual analogue scale, ODI Oswestry Disability Index, ADC apparent diffusion coefficient, ND not determined