Fig. 4
From: Thioredoxin mitigates radiation-induced hematopoietic stem cell injury in mice
TXN facilitates expansion of hematopoietic progenitor cells and increases bone marrow cellularity. The effects of thioredoxin (TXN) on the colongenic function of HSCs in bone marrow were measured by CFU assay in total body irradiation (TBI) mice for a colony forming unit-granulocyte macrophage (CFU-GM) and b colony forming unit-granulocyte, erythroid, macrophage, megakaryocyte (CFU-GEMM). c Effects of TXN on bone marrow cellularity in TBI mice. Panels show H&E staining of mouse femurs. Representative images are shown for saline and TXN treatments. Data are shown as the mean ± SD. *P < 0.05. n.s. not significant