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Table 1 In-vivo studies with MHC controls and immune response analysis

From: Immunoprivileged no more: measuring the immunogenicity of allogeneic adult mesenchymal stem cells

Author

Species

Cell-mediated

Humoral

In vivo rejection

Methods used

Eliopoulos and Stagg, 2005 [29]

Mouse

+

 

+

In-vivo cytotoxicity

Nauta et al., 2006 [30]

Mouse

+

 

+

In-vivo cytotoxicity

Badillo et al., 2007 [31]

Mouse

+

+

 

Ex-vivo MLR, allograft rejection

Poncelet et al., 2007 [32]

Pig

+

+

 

Ex-vivo MLR, CDC

Zangi et al., 2009 [33]

Mouse

+

+

+

Allograft rejection, in-vivo imaging

Isakova et al., 2014 [34]

Rhesus Macaques

+

  

In-vitro cytotoxicity

Pezzanite et al., 2015 [35]

Horse

 

+

 

CDC

  1. CDC complement-dependent cytotoxicity, MHC major histocompatibility complex, MLR mixed leukocyte reaction