Hepatic stem cells with self-renewal and liver repopulation potential are harbored in CDCP1-positive subpopulations of human fetal liver cells

Table 1 Bipotential capability in single HpSC-derived colonies during serial sorting

Serial sorting	Single ALB⁺ (%)	Single CK7⁺ (%)	Double negative (%)	Double positive (%)
First	0.3 ± 0.9	18.6 ± 13.0	9.1 ± 4.7	72.0 ± 11.8
Second	0.1 ± 0.1	10.3 ± 6.6	8.1 ± 5.3	81.5 ± 9.8
Third	03 ± 0.6	2.7 ± 3.0	6.7 ± 4.0	90.3 ± 2.5
Fourth	0.0	12.9 ± 9.1	9.6 ± 7.4	77.5 ± 10.8

Immunostaining of human ALB and human CK7 in HpSC colonies derived from the first, second, third, and fourth sorting performed as described in Fig. 4c. Numbers represent percentage of ALB and/or CK7 stained or not stained in each colony. Results shown as mean percentage ± SD (n = 3 independent experiments)
ALB Albumin, CK cytokeratin, HpSC hepatic stem cell

ISSN: 1757-6512