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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Human umbilical cord mesenchymal stem cell conditioned medium attenuates renal fibrosis by reducing inflammation and epithelial-to-mesenchymal transition via the TLR4/NF-κB signaling pathway in vivo and in vitro

Fig. 3

Effects of hucMSC-CM on UUO-induced TNF-α, IL-1β, and IL-6 in serum and kidney tissues. hucMSC-CM inhibited the increase of TNF-α, IL-1β, and IL-6 in UUO-induced rats. Values presented as mean ± SD. UUO group compared with Sham, Control, and hucMSC-CM groups. Values statistically significant at: *P < 0.05, Sham and Control groups compared with UUO and hucMSC-CM groups; #P < 0.05. CM conditioned medium, hucMSC human umbilical cord-derived mesenchymal stem cell, IL interleukin, TNF tumor necrosis factor, UUO unilateral ureteral obstruction

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Stem Cell Research & Therapy

ISSN: 1757-6512