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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: RETRACTED ARTICLE: hPMSC transplantation restoring ovarian function in premature ovarian failure mice is associated with change of Th17/Tc17 and Th17/Treg cell ratios through the PI3K/Akt signal pathway

Fig. 4

IHC analysis on PI3K, Akt, p-Akt and capase-3 in ovarian tissue of mice. Photomicrographs (400×) show hematoxylin and DAB-stained ovaries. (a1-d1) Control group (C group). (a2-d2) POF group (M group). (a3-d3) POF + hPMSCs group (T group). (a4-d4) POF + hPMSCs + LY294002 group (L group). (a5-d5) POF + hPMSCs + DMSO group (D group). The statistical charts of the four kinds of cytokines expression in the five groups (a6-d6). Brown in cytoplasm indicates positive expression of the aimed protein. Blue represents cell nuclear staining. **P < 0.01, ***P < 0.001 vs POF group. Bar scale = 50 μm. POF premature ovarian failure, hPMSC human placenta-derive mesenchymal stem cell, DMSO dimethylsulfoxide, PI3K phosphatidylinositol 3-kinase

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Stem Cell Research & Therapy

ISSN: 1757-6512