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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Human mesenchymal stem cells in spheroids improve fertility in model animals with damaged endometrium

Fig. 4

Decidual differentiation of eMSC spheroids. a eMSC spheroids, control cells; b eMSC spheroids, treated with 1 mM 8-Br-cAMP for 7 days; c, d ELISA assay of prolactin (c) and IGFBP-1 (d) secretion of control and induced to decidual differentiation eMSC spheroids and monolayer cells. Data are shown as mean ± SD. Two-tailed Students t test was utilized for pairwise comparison. *p < 0.01 vs. control undifferentiated cells. eMSC endometrial mesenchymal stem cells, IGFBP-1 insulin-like growth factor binding protein-1

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Stem Cell Research & Therapy

ISSN: 1757-6512