Fig. 6
From: Engineering a multicellular vascular niche to model hematopoietic cell trafficking
Leukemic cells perfused alone respond to microenvironmental cues. a Leukemic CD34+ cells perfused through unmodified, HS5-, and HS27a-modified vessels adhere and migrate. b Visualization of the leukemic cells with regards to the vessel walls (yellow dotted lines). Blue = nuclei, scale bars = 100 μm. c Quantification of adhesion and migration of leukemic cells. Significant differences are shown between unmodified (endothelial cell; EC) and stromal conditions unless marked. *p < 0.05, **p < 0.01