Table 1 Correlation between TBX21 expression and different clinical characteristics in LUAD patients enrolled in the study
Variable | Low TBX21 expression group | HighTBX21 expression group | P value# |
|---|---|---|---|
GSE50081 | |||
Stage | 0.385 | ||
I | 37 (78.7%) | 45 (71.4%) | |
≥ II | 10 (21.3%) | 18 (28.6%) | |
Age | 0.245 | ||
< 65 years | 14 (26.4%) | 23 (36.5%) | |
≥ 65 years | 39 (73.6%) | 40 (63.5%) | |
Gender | 0.877 | ||
Female | 26 (49.1%) | 30 (47.6%) | |
Male | 27 (50.9%) | 33 (52.4%) | |
Smoking | 0.364 | ||
No | 11 (20.8%) | 9 (14.3%) | |
Yes | 35 (66.0%) | 49 (77.8%) | |
NA | 7 (13.2%) | 5 (7.9%) | |
GSE31210 | |||
Stage | 0.296 | ||
I | 74 (78.7%) | 45 (71.4%) | |
≥ II | 20 (21.3%) | 18 (28.6%) | |
Age | 0.107 | ||
< 65 years | 71 (74.0%) | 39 (61.9%) | |
≥ 65 years | 25 (26.0%) | 24 (38.1%) | |
Gender | 0.382 | ||
Female | 51 (53.1%) | 29 (46.0%) | |
Male | 45 (46.9%) | 34 (54.0%) | |
Smoking | 0.419 | ||
No | 52 (54.2%) | 30 (47.6%) | |
Yes | 44 (45.8%) | 33 (52.4%) | |
GSE30219 | |||
Stage | 0.801 | ||
I | 27 (87.1%) | 34 (85%) | |
≥ II | 4 (12.9%) | 6 (15%) | |
Age | 0.583 | ||
< 65 years | 19 (73.1%) | 26 (66.7%) | |
≥ 65 years | 7 (26.9%) | 13 (33.3%) | |
Gender | 0.376 | ||
Female | 9 (29.0%) | 8 (20.0%) | |
Male | 22 (71.0%) | 32 (80.0%) | |
GSE68465 | |||
Stage | 0.448 | ||
I | 62 (36.3%) | 55 (32.4%) | |
≥ II | 109 (63.7%) | 115 (67.6%) | |
Age | 0.746 | ||
< 65 years | 85 (49.7%) | 82 (48.0%) | |
≥ 65 years | 86 (50.3%) | 89 (52.0%) | |
Gender | 0.175 | ||
Female | 81 (47.4%) | 93 (54.7%) | |
Male | 90 (52.6%) | 77 (45.3%) | |
Smoking | 0.105 | ||
No | 19 (11.1%) | 22 (12.9%) | |
Yes | 108 (63.2%) | 121 (70.8%) | |
NA | 44 (25.7%) | 28 (16.3%) | |
GSE72094 | |||
Stage | 0.570 | ||
I | 99 (63.5%) | 88 (66.7%) | |
≥ II | 57 (36.5%) | 44 (33.3%) | |
Age | 0.207 | ||
< 65 years | 51 (30.0%) | 31 (23.5%) | |
≥ 65 years | 119 (70.0%) | 101 (76.5%) | |
Gender | 0.955 | ||
Female | 92 (54.1%) | 71 (53.8%) | |
Male | 78 (45.9%) | 61 (46.2%) | |
Smoking | 0.103 | ||
No | 21 (12.4%) | 7 (5.3%) | |
Yes | 122 (71.8%) | 100 (75.8%) | |
NA | 27 (15.8%) | 25 (18.9%) | |
TCGA LUAD | |||
Stage | 0.805 | ||
I | 114 (59.1%) | 118 (57.8%) | |
≥ II | 79 (40.9%) | 86 (42.2%) | |
Age | 0.022* | ||
< 65 years | 95 (47.5%) | 7 (5.3%) | |
≥ 65 years | 98 (49.0%) | 100 (75.8%) | |
NA | 27 (15.8%) | 25 (18.9%) | |
Gender | 0.337 | ||
Female | 104 (52.0%) | 113 (56.8%) | |
Male | 96 (48.0%) | 86 (43.2%) | |
Smoking | 0.056 | ||
No | 71 (35.5%) | 53 (26.6%) | |
Yes | 129 (64.5%) | 146 (73.4%) | |