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Table 1 Correlation between TBX21 expression and different clinical characteristics in LUAD patients enrolled in the study

From: TBX21 predicts prognosis of patients and drives cancer stem cell maintenance via the TBX21–IL-4 pathway in lung adenocarcinoma

Variable Low TBX21 expression group HighTBX21 expression group P value#
GSE50081
 Stage    0.385
  I 37 (78.7%) 45 (71.4%)  
  ≥ II 10 (21.3%) 18 (28.6%)
 Age    0.245
  < 65 years 14 (26.4%) 23 (36.5%)  
  ≥ 65 years 39 (73.6%) 40 (63.5%)
 Gender    0.877
  Female 26 (49.1%) 30 (47.6%)  
  Male 27 (50.9%) 33 (52.4%)
 Smoking    0.364
  No 11 (20.8%) 9 (14.3%)  
  Yes 35 (66.0%) 49 (77.8%)
  NA 7 (13.2%) 5 (7.9%)
GSE31210
 Stage    0.296
  I 74 (78.7%) 45 (71.4%)  
  ≥ II 20 (21.3%) 18 (28.6%)
 Age    0.107
  < 65 years 71 (74.0%) 39 (61.9%)  
  ≥ 65 years 25 (26.0%) 24 (38.1%)
 Gender    0.382
  Female 51 (53.1%) 29 (46.0%)  
  Male 45 (46.9%) 34 (54.0%)
 Smoking    0.419
  No 52 (54.2%) 30 (47.6%)  
  Yes 44 (45.8%) 33 (52.4%)
GSE30219
 Stage    0.801
  I 27 (87.1%) 34 (85%)  
  ≥ II 4 (12.9%) 6 (15%)
 Age    0.583
  < 65 years 19 (73.1%) 26 (66.7%)  
  ≥ 65 years 7 (26.9%) 13 (33.3%)
 Gender    0.376
  Female 9 (29.0%) 8 (20.0%)  
  Male 22 (71.0%) 32 (80.0%)
GSE68465
 Stage    0.448
  I 62 (36.3%) 55 (32.4%)  
  ≥ II 109 (63.7%) 115 (67.6%)
 Age    0.746
  < 65 years 85 (49.7%) 82 (48.0%)  
  ≥ 65 years 86 (50.3%) 89 (52.0%)
 Gender    0.175
  Female 81 (47.4%) 93 (54.7%)  
  Male 90 (52.6%) 77 (45.3%)
 Smoking    0.105
  No 19 (11.1%) 22 (12.9%)  
  Yes 108 (63.2%) 121 (70.8%)
  NA 44 (25.7%) 28 (16.3%)
GSE72094
 Stage    0.570
  I 99 (63.5%) 88 (66.7%)  
  ≥ II 57 (36.5%) 44 (33.3%)
 Age    0.207
  < 65 years 51 (30.0%) 31 (23.5%)  
  ≥ 65 years 119 (70.0%) 101 (76.5%)
 Gender    0.955
  Female 92 (54.1%) 71 (53.8%)  
  Male 78 (45.9%) 61 (46.2%)
 Smoking    0.103
  No 21 (12.4%) 7 (5.3%)  
  Yes 122 (71.8%) 100 (75.8%)
  NA 27 (15.8%) 25 (18.9%)
TCGA LUAD
 Stage    0.805
  I 114 (59.1%) 118 (57.8%)  
  ≥ II 79 (40.9%) 86 (42.2%)
 Age    0.022*
  < 65 years 95 (47.5%) 7 (5.3%)  
  ≥ 65 years 98 (49.0%) 100 (75.8%)
  NA 27 (15.8%) 25 (18.9%)
 Gender    0.337
  Female 104 (52.0%) 113 (56.8%)  
  Male 96 (48.0%) 86 (43.2%)
 Smoking    0.056
  No 71 (35.5%) 53 (26.6%)  
  Yes 129 (64.5%) 146 (73.4%)
  1. LUAD lung adenocarcinoma, TCGA The Cancer Genome Atlas, NA not available
  2. #Pearson’s chi-square test
  3. *Fisher’s exact test