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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Characterization of the interaction between human decidua parietalis mesenchymal stem/stromal cells and natural killer cells

Fig. 6

Flow cytometric analysis of the indicated activating and inhibiting receptors by natural killer (NK) cells harvested from NK/DPMSC cytolytic experiments. Decidua parietalis mesenchymal stem/stromal cells (DPMSCs) significantly increased NK cell expression of DNAM (a) and NKp46 (b), while the expression of CD94 (c) and CD69 (d) was significantly decreased. DPBMSCs had no significant effect on NK cell expression of NKp30 (e), NKp44 (f), and NKG2D (g) (P > 0.05). The levels of the expression of activating and inhibitory receptors in NK cells were recorded as median fluorescence intensity (MFI) as determined by flow cytometry. Experiments were carried out in triplicate and repeated 10 times using NK cells and DPMSCs prepared from the peripheral blood of 10 different healthy donors and 10 different fetal membranes, respectively. Bars represent standard errors. *P < 0.05, versus untreated NK cells

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