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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Expression profiling of cell-intrinsic regulators in the process of differentiation of human iPSCs into retinal lineages

Fig. 8

Differentially expressed components of epigenetic complexes. a Hierarchical clustering of genes encoding components of PcG complexes. b Hierarchical clustering of genes encoding components of COMPASS/MLL complexes. c Hierarchical clustering of genes encoding components of SWI/SNF complexes. d qRT-PCR validation of expression patterns of ACTL6B, PCGF5 and CECR2 genes using same RNA as used for microarray (left) and RNA obtained from independent set of cells (right) that included two stages of differentiation of RGCs (9 and 17 days post OV), hiPSC-derived RPE cells (RPE) and RPE cell line ARPE-19. FC fold-change, OV optic vesicle, RGC retinal ganglion cell, RPE retinal pigment epithelium

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Stem Cell Research & Therapy

ISSN: 1757-6512