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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: α6-Integrin alternative splicing: distinct cytoplasmic variants in stem cell fate specification and niche interaction

Fig. 2

Summary of the potential signal pathways involved in regulation of stem cell fate by distinct α6 cytoplasmic variants. Current findings suggest that α6A functions to promote stem cell differentiation in various stem cell populations via specific signal pathways. α6B mediates VEGF- and/or LM511-dependent signals to promote the self-renewal of breast CSCs

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