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Fig. 10 | Stem Cell Research & Therapy

Fig. 10

From: Early gestational mesenchymal stem cell secretome attenuates experimental bronchopulmonary dysplasia in part via exosome-associated factor TSG-6

Fig. 10

Schematic representation of MSC-CM/EXO/TSG-6 treatment regimen and outcomes in the mouse model of BPD. BPD pathology is reversed in the pups injected with secretome of hUC-derived MSCs. This therapeutic effect is mediated, at least in part, by exosomal factor TSG-6. BPD bronchopulmonary dysplasia, CM conditioned medium, EXO exosomes, hUC human umbilical cord, i.p. intraperitoneal, MSC mesenchymal stem cell, PN postnatal, TSG-6 tumor necrosis factor alpha-stimulated gene-6

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Stem Cell Research & Therapy

ISSN: 1757-6512