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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Prevascularization promotes endogenous cell-mediated angiogenesis by upregulating the expression of fibrinogen and connective tissue growth factor in tissue-engineered bone grafts

Fig. 6

Prevascularization increased number of vWF+ endogenous cells and neonatal capillary-like structures. a Immunofluorescence images of vWF (red) and EGFP (green) from TEBG sections and prevascularized TEBG sections at 1 and 4 weeks after transplantation. White arrows, double-positive staining cells. Hoechst 33342 stained nuclei blue; scale bars = 50 μm. b Number of vWF+ cells overlaid with EGFP+ endogenous cells, n = 6. c Number of capillary-like structures (mm2) and length (μm), n = 6. Data presented as mean ± s.e.m. **P < 0.01 determined by Student t tests. EGFP enhanced green fluorescent protein, TEBG tissue-engineered bone graft vWF von Willebrand factor

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