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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Exosomes derived from human adipose mesenchymal stem cells improve ovary function of premature ovarian insufficiency by targeting SMAD

Fig. 6

hADSC-Exos upregulated SMAD pathway in POI hGCs. a qPCR analysis of mRNA expression levels of SMAD2, SMAD3, and SMAD5 after hADSC-Exos coculture with POI hGCs. b Western blot analysis of protein expression levels of SMAD2, SMAD3, and SMAD5 after hADSC-Exos coculture with POI hGCs. Error bars indicate SD. ***p < 0.001 (compared with normal group); ###p < 0.001 (compared with hADSC-Exos treatment group). POI premature ovarian insufficiency, PBS phosphate buffered saline, hADSC human adipose mesenchymal stem cells, GAPDH glyceraldehyde 3-phosphate dehydrogenase, EXO exosome

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Stem Cell Research & Therapy

ISSN: 1757-6512