Decellularized human ovarian scaffold based on a sodium lauryl ester sulfate (SLES)-treated protocol, as a natural three-dimensional scaffold for construction of bioengineered ovaries

Table 2 Primary ovarian cells seeded on decellularized ovary scaffold restore serum estradiol and progesterone levels in ovariectomized rats after transplantation

	non-OVX	POCs-DS	OVX-C	DS
Estradiol (pg/mL)	66.47 ± 7.02^*	41.69 ± 2.44**	19.54 ± 1.57	21.092 ± 1.69
Progesterone (ng/mL)	36.67 ± 1.79	31.17 ± 3.35^#	7.51 ± 1.26	7.91 ± 2.67

Results are presented as mean ± S.E.M (standard error of the mean); n = 4 in each group. Non-OVX non-ovariectomized group, OVX-C ovariectomized control group, POCs-DS primary ovarian cells seeded decellularized scaffolds recipient group, DS decellularized scaffolds recipient group. Significance was calculated using one-way analysis of variance (ANOVA) with Tukey’s multiple comparison test. p values < 0.05 were considered as statistically significant
^*Indicates p < 0.005, Non-OVX vs. the other groups
^**Indicates p < 0.018, POCs-DS vs. OVX-C and DS
^#Indicates p < 0.0003, POCs-DS vs. OVX-C and DS

ISSN: 1757-6512