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Table 2 Primary ovarian cells seeded on decellularized ovary scaffold restore serum estradiol and progesterone levels in ovariectomized rats after transplantation

From: Decellularized human ovarian scaffold based on a sodium lauryl ester sulfate (SLES)-treated protocol, as a natural three-dimensional scaffold for construction of bioengineered ovaries

  non-OVX POCs-DS OVX-C DS
Estradiol (pg/mL) 66.47 ± 7.02* 41.69 ± 2.44** 19.54 ± 1.57 21.092 ± 1.69
Progesterone (ng/mL) 36.67 ± 1.79 31.17 ± 3.35# 7.51 ± 1.26 7.91 ± 2.67
  1. Results are presented as mean ± S.E.M (standard error of the mean); n = 4 in each group. Non-OVX non-ovariectomized group, OVX-C ovariectomized control group, POCs-DS primary ovarian cells seeded decellularized scaffolds recipient group, DS decellularized scaffolds recipient group. Significance was calculated using one-way analysis of variance (ANOVA) with Tukey’s multiple comparison test. p values < 0.05 were considered as statistically significant
  2. *Indicates p < 0.005, Non-OVX vs. the other groups
  3. **Indicates p < 0.018, POCs-DS vs. OVX-C and DS
  4. #Indicates p < 0.0003, POCs-DS vs. OVX-C and DS
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Stem Cell Research & Therapy

ISSN: 1757-6512