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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: miR-431 inhibits adipogenic differentiation of human bone marrow-derived mesenchymal stem cells via targeting insulin receptor substance 2

Fig. 5

IRS2 promotes adipogenesis of hMSCs. a The mRNA expression levels of insulin receptor substance 2 (IRS2) in hMSCs infected by IRS2 small interfering RNA (siRNA) lentivirus or negative control (NC) lentivirus. b The protein expression levels of IRS2 in hMSCs infected by IRS2 siRNA lentivirus or NC lentivirus. c Oil Red O staining of hMSCs infected by IRS2 siRNA lentivirus or NC lentivirus. d The mRNA expression levels of CCAAT/enhancer binding protein α (C/EBPα) and peroxisome proliferator-activated receptor γ (PPARγ) in hMSCs infected by IRS2 siRNA lentivirus or NC lentivirus. e The protein expression levels of C/EBPα and PPARγ in hMSCs infected by IRS2 siRNA lentivirus or NC lentivirus. Data are presented as the mean ± SEM (n = 3). *p < 0.05, **p < 0.01, versus NC

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Stem Cell Research & Therapy

ISSN: 1757-6512