Fig. 6

IRS2 rescues the adipogenesis of hMSCs inhibited by miR-431. a The mRNA expression levels of CCAAT/enhancer binding protein α (C/EBPα) and peroxisome proliferator-activated receptor γ (PPARγ) in hMSCs infected by miR-431 lentivirus alone (miR431) or combined with insulin receptor substance 2 (IRS2) expression vector (miR431 + IRS2). b The protein expression levels of C/EBPα and PPARγ in hMSCs infected by miR-431 lentivirus alone (miR431) or combined with IRS2 expression vector (miR431 + IRS2). Data are presented as the mean ± SEM (n = 3). *p < 0.05, versus miR-431 lentivirus alone