Fig. 7
From: The effect of acute respiratory distress syndrome on bone marrow-derived mesenchymal stem cells
Secretion profile of MSCs cocultured with MNCs in response to LPS treatment. ‘Injured’ MSCs exhibit diminished capacity to secrete interleukin (IL)-1α and IL-1ra compared with mononuclear cells (MNCs) (p < 0.01) as well as reduced capacity to secrete IL-10 and IL-12 compared with ‘Uninjured’ MSCs (p < 0.05); all MSCs were able to significantly both secrete high levels of IL-6 and suppress tumor necrosis factor (TNF)-α production compared with MNCs alone (p < 0.0001). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. TP total protein