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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Gene expression profiling of chondrogenic differentiation by dexamethasone-conjugated polyethyleneimine with SOX trio genes in stem cells

Fig. 6

Expression level of mRNA of members of the collagen and MMP families in transfected hMSCs. a Heatmap showing the expression of various members of the collagen and MMP families in each group of hMSCs relative to that in nontreated hMSCs. b RT-PCR analysis of COLI, COLII, MMP3, and MMP13 in each group of hMSCs. c Bar graphs of the mRNA levels of COLI, COLII, MMP3, and MMP13. The hMSCs transfected with nothing (panel a), DEX/PEI only (panel b), SOX5-complexed DEX/PEI (panel c), SOX6-complexed DEX/PEI (panel d), SOX9-complexed DEX/PEI (panel e), and SOX5/6/9 (trio) complexed DEX/PEI (DI-NPs) (panel f). n = 5. COL collagen, MMP matrix metallopeptidase

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