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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Knockdown of insulin-like growth factor 1 exerts a protective effect on hypoxic injury of aged BM-MSCs: role of autophagy

Fig. 5

IGF-1 knockdown decreased the activity of the Akt/mTOR signaling pathway in aged BM-MSCs. a Representative western blots of p-Akt/Akt and p-mTOR/mTOR in aged BM-MSCs. b Representative western blots of p-p70S6, K/p70S6 K, and p-S6/S6 in aged BM-MSCs. Semiquantification of the protein expression levels of p-Akt (c), p-mTOR (d) (n = 5, *p < 0.05). Semiquantification of the protein expression levels of p-p70S6 K/p70S6 K (e) and p-S6/S6 (f) (n = 5, *p < 0.05)

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Stem Cell Research & Therapy

ISSN: 1757-6512