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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: LincRNA-p21 promotes mesenchymal stem cell migration capacity and survival through hypoxic preconditioning

Fig. 5

The effect of knock down of LincRNA-p21 on hypoxic preconditioning-induced MSC migration. To investigate the role of LincRNA-p21 on hypoxic preconditioning induced MSC migration, we introduced shLincRNA-p21 and used hypoxic preconditioning (1% O2) induced MSCs migration at 24 h, which were tested by scratch healing and transwell migration assays (stained with crystal violet). a The effect of knock down of LincRNA-p21 on hypoxic preconditioning-induced MSC migration in scratch healing analysis at 24 h (400-fold magnification). b Healing area ratio in scratch healing analysis at 24 h. c The effect of knock down of LincRNA-p21 on hypoxic preconditioning induced MSC transwell migration at 24 h (400-fold magnification). d Cell counts of transwell migration at 6 h and 12 h. Results are mean ± SD (n = 3). *p < 0.05 vs. comparison group

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Stem Cell Research & Therapy

ISSN: 1757-6512