Fig. 1
Characterization of preconditioned MSCs. MSCs were cultured in the presence of 30 ng/ml IFN-ɣ and 3 ng/ml IL-1ß for 24 h. a iNOS gene expression was analyzed by real-time PCR. n = 3, *p < 0.05. b Nitrite (NO2) levels in culture supernatants were quantified by Griess assay. n = 9, ***p < 0.001. c TGF-ß (n = 4), IL-6 (n = 6) and PGE2 (n = 5) levels in culture supernatants were quantified by ELISA. *p < 0.05; ***p < 0.001. IL interleukin, MSCs mesenchymal stem cells, iNOS inducible nitric oxide synthase, PGE2 prostaglandin E2, TGF-ß tumor growth factor beta